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| retinopathy of prematurity ： ウィキペディア英語版 |
retinopathy of prematurity
Retinopathy of prematurity (ROP) or Terry syndrome, previously known as retrolental fibroplasia (RLF), is a disease of the eye affecting prematurely-born babies generally having received intensive neonatal care, in which oxygen therapy is used on them due to the premature development of their lungs. It is thought to be caused by disorganized growth of retinal blood vessels which may result in scarring and retinal detachment. ROP can be mild and may resolve spontaneously, but it may lead to blindness in serious cases. As such, all preterm babies are at risk for ROP, and very low birth weight is an additional risk factor. Both oxygen toxicity and relative hypoxia can contribute to the development of ROP.
==Causes==
By the fourth month of pregnancy, the unborn child's retina has begun to develop vascularization. Such formation of blood vessels appears to be very sensitive to the amount of oxygen supplied, either naturally or artificially. In rare cases it has been found in some patients with ROP a mutation in the NDP gene, which is normally associated with the more formidable Norrie disease.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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